二氢乳清酸脱氢酶（DHODH）已被证实是程序性细胞死亡的关键调控因子，但其在巨自噬/自噬中的作用尚不明确。黄病毒科病毒对全球公共卫生构成重大威胁，其复制过程与自噬密切相关。

复发性妊娠丢失（RPL）是一种多因素病症，其特征为连续发生两次或两次以上的妊娠丢失，影响约1-2%的备孕夫妇。尽管生殖医学已取得诸多进展，仍有大量RPL病例病因不明（URPL），这使其成为 诊断 与治疗领域的重大挑战。

痘病毒科（Poxviridae）是一类重要的人兽共患病原体，猴痘病毒、牛结节性皮肤病病毒等持续威胁公共卫生与畜牧养殖业安全。自噬（autophagy）是一种在进化上具有保守性的、多步骤的细胞内生物学过程，它参与了众多生理和病理过程，包括对病毒感染的防 ...

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Autophagy has been shown to be a key player in preventing aging and diseases of aging, including cancer, cardiovascular disease, diabetes, and neurodegeneration. Notably, research has shown that ...