Prolonged storage of transfused red blood cells (RBCs) is associated with hemolysis in healthy adults and inflammation in animal models. We aimed to determine whether storage duration affects markers ...

The phase 3 PEGASUS trial found that patients with paroxysmal nocturnal hemoglobinuria (PNH) may still experience anemia following recommended therapies, underscoring the need for further research. In ...

THE sequence of hemoglobinuria followed by oliguria and anuria is well known. The observations reported below are especially concerned with the medical management of the anuric patient and with the ...

CHRONIC lymphocytic leukemia and malignant lymphomas of the lymphocytic and follicular types may be relatively prolonged, benign diseases. They are inevitably fatal, however, and the final years are ...

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme. Free heme can cause significant inflammation and ...

red blood cells The FDA has granted Priority Review for the Biologics License Application (BLA) for sutimlimab for the treatment of hemolysis in adult patients with cold agglutinin disease, a rare ...

Researchers have discovered how hemolysis causes infections, and have found a new means to prevent it, paving the way to new treatment possibilities. For decades, iron has been considered the prime ...

A research team from The Netherlands investigated the consequences of hemolysis for intestinal blood flow and its possible association with intestinal injury. They found that intestinal injury was ...

Voydeya is a first-in-class, oral, factor D inhibitor. The Food and Drug Administration (FDA) has approved Voydeya ™ (danicopan) as add-on therapy to ravulizumab or eculizumab for the treatment of ...

Hemolysis is the #1 source of preanalytical error and can impact potassium results—potentially leading to inappropriate or delayed patient treatment, unnecessary ...

Hemolysis is a common pre-analytical variable that can lead to inaccurate results, specimen rejection, and specimen recollection in the clinical laboratory. Hemolysis is most often an in vitro ...