Cleveland, OH - A new study published this week provides evidence of a mechanistic link between a variant of the paraoxonase 1 (PON1) gene and cardiovascular disease events [1]. Investigators showed ...

To estimate the arylesterase activity of serum paraoxonase-1 (PON1-ARE), which is reported to have an antioxidant and antiatherogenic potential and to correlate with plasma homocysteine (Hcys) and ...

The gene for the HDL-associated protein paraoxonase 1 appears to be associated with coronary artery disease and with the risk of developing adverse cardiac events, and variations in both the PON1 gene ...

There is growing evidence that cardiovascular health can be affected by exposure to methylmercury (MeHg), by a mechanism involving oxidative stress. Paraoxonase 1 (PON1) is a high-density ...

INTRODUCTION: Obesity is an important risk factor for atherosclerotic cardiovascular disease. Paraoxonase‑1 (PON1) may play a significant role in the prevention of obesity‑related accelerated ...

May 5, 2011 (Munich, Germany) — A new study has refuted previous data suggesting that PON1 gene polymorphisms are involved in the activation of clopidogrel [1]. The study, published online April 28, ...

DALLAS, May 20 – An oxidation-fighting enzyme called paraoxonase (PON1) can significantly reduce the risk of heart attacks, according to research reported in today’s rapid access issue of Circulation: ...

The gene for the HDL-associated protein paraoxonase 1 (PON1) appears to be associated with coronary artery disease and with the risk of developing adverse cardiac events, and variations in both the ...