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生物通
4 个月
由Echinocactus grusonii Hildm.产生的代谢物对乙酰胆碱酯酶和β-分泌酶的 ...
从埃及仙人掌Echinocactus grusonii中分离出七种化合物,包括黄酮类、单萜苷和新型卤代生物碱。所有化合物均显著抑制AChE(IC50范围0.076–2.255 μg/mL)和β-分泌酶(IC50范围0.066–7.189 μg/mL),其中化合物和的抑制活性最佳,且计算化学和分子动力学模拟证实其与酶 ...
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