In the ever-evolving field of health and medicine, researchers are constantly seeking new ways to improve treatments and enhance the quality of life. One such discovery that is gaining significant ...

From PCR and CRISPR to autophagy and targeted cancer therapies, scientists share the discoveries that shaped their work and ...

Researchers in Spain have found that chaperone-mediated autophagy, a selective protein cleanup process, is markedly reduced in the motor neurons of ALS patients. The deficiency may contribute to toxic ...

Researchers have reported major advances in understanding and treating ALS and Parkinson’s disease, with potential to reshape ...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which ...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which ...

Studies in yeast, flies and mice have shown that relatively low doses of rapamycin often increase the creatures’ lifespans.

二氢乳清酸脱氢酶（DHODH）已被证实是程序性细胞死亡的关键调控因子，但其在巨自噬/自噬中的作用尚不明确。黄病毒科病毒对全球公共卫生构成重大威胁，其复制过程与自噬密切相关。

Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...

复发性妊娠丢失（RPL）是一种多因素病症，其特征为连续发生两次或两次以上的妊娠丢失，影响约1-2%的备孕夫妇。尽管生殖医学已取得诸多进展，仍有大量RPL病例病因不明（URPL），这使其成为 诊断 与治疗领域的重大挑战。

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.