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Interactions of the extracellular matrix (ECM) and cellular receptors constitute one of the crucial pathways involved in colorectal cancer progression and metastasis. With the use of bioinformatics ...
We are developing a workflow that involves mapping sets of short nc RNA reads to the miRBase (mature micro RNAs) database. We would like to use STAR for this alignment. We have adjusted the genome ...
MicroRNAs (miRNAs) are evolutionary conserved small non-coding RNA molecules that post-transcriptionally regulate gene expression by base-pairing to mRNAs. Recent evidence shows that miRNA-mediated ...
相信,基因信息检索涉及到我们每个科研实验人员每天的日常实验中,而用的多的几个数据库莫过于NCBI RefSeq,Ensemble,mirBase三个数据库。那这三个数据库中基因信息都是根据什么规则来命名的呢? 一、NCBI RefSeq NCBI RefSeq(美国国立生物技术信息中心参考序列库)是 ...
Degradome sequencing (degradome-seq) was widely used for cleavage site mapping on the microRNA (miRNA) targets. Here, the application value of degradome-seq data in tracking the miRNA processing ...
沉寂4年,miRBase终于在2018年3月12日发布了v22 版本。时隔四年,miRBase数据库究竟发生了怎样的变化呢?对我们的研究又会带来什么样的影响呢?来,让我们一起走近它,看看它的美! miRBase序列数据库 (www.mirbase.org) 是关于miRNA全方位数据的一个重要公共数据库 ...
MicroRNAs (miRNAs) are small ∼22-nt RNAs that are important regulators of posttranscriptional gene expression. Since their initial discovery, they have been shown to be involved in many cellular ...
Small RNAs are pivotal regulators of gene expression that guide transcriptional and post-transcriptional silencing mechanisms in eukaryotes, including plants. Here we report a comprehensive atlas of ...
miRBase is the public repository for all published microRNA sequences and associated annotation. miRBase was established in 2002, then called the MicroRNA Registry, with the primary aim of assigning ...
We describe an update of the miRBase database (http://www.mirbase.org/), the primary microRNA sequence repository. The latest miRBase release (v20, June 2013 ...
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