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Why Acid Chlorides are the Most Reactive Carboxylic Acid Derivatives
Why do acid chlorides react with almost any nucleophile? Comment WORKSHEET and I’ll send you practice to lock this in. This video breaks down the mechanism of nucleophilic acyl substitution and shows why chloride is the key. As a large, stable leaving group, Cl⁻ is easily kicked out, making acid chlorides far more reactive than other ...
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